Research articles
ScienceAsia (): 262-267 |doi:
10.2306/scienceasia1513-1874...262
Sebumetric and mexametric evaluation of a fennel based cream
Akhtar Rasula,b,*, Naveed Akhtara, Muhammad Iqbalb, Barkat Ali Khana, Asadullah Madnia, Ghulam Murtazac, Muhammad Khurram Waqasa, Tariq Mahmooda
ABSTRACT: This study aims to investigate the effects of a topical cream (emulsion) containing 4% extract of fennel (Foeniculum vulgare) on functional skin parameters like sebum content, skin melanin, and skin erythaema, using the base without fennel as a control. Fennel extract was entrapped in the inner aqueous phase of emulsion. The creams were applied to 11 healthy male volunteers for a period of 12 weeks. Skin parameters were measured fortnightly using a Mexameter MPA 5 and a Sebumeter MPA 5 to determine the effects produced. The base showed insignificant (p>0.05) increase while the active formulation showed significant (p≤0.05) decrease in skin melanin and sebum content, which can be attributed to the presence of linoleic acid and oleic acids in fennel. Analysis using a paired sample t-test showed that the base decreased skin erythaema insignificantly while the formulation exerted a significant decrease indicating that it possessed anti-erythaemic effects. The formulation can therefore be used safely for the treatment of acne and as a skin whitening agent in males.
Download PDF
45 Downloads 1323 Views
| a |
Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur 63100 Pakistan |
| b |
School of Pharmacy, The University of Faisalabad, Faisalabad 37610 Pakistan |
| c |
Department of Pharmacy, COMSATS Institute of Information Technology, Abbotabad, Pakistan |
* Corresponding author, E-mail: dr.akhtarstar@gmail.com
Received 24 Dec 2011, Accepted 1 May 2012
|
