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Research Article
ScienceAsia 29 (2003): 021-030 |doi: 10.2306/scienceasia1513-1874.2003.29.021
Chemical Constituents from the Flowers of
Nyctanthes arbor-tristis
Pittaya Tuntiwachwuttikula,*, Kanokon Rayanila and Walter C Taylorb
ABSTRACT: Activity guided fractionation of an ethanol extract from the flowers of Nyctanthes arbor-tristis led
to the isolation of an antiplasmodial cyclohexylethanoid, rengyolone (1); a new iridoid glucoside, 6-Otrans-
cinnamoyl-7-O-acetyl-6b-hydroxyloganin (2); and three known iridoid glucosides, arborside C (4 4),
6b-hydroxyloganin (6) and nyctanthoside (7). Compound 1 and its acetate derivative (1a 1a) exhibited
antiplasmodial activity against Plasmodium falciparum. Chemical structures of 2 and its acetate (2a 2a) were
elucidated by spectral analyses.
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a Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom 73000, Thailand.
b School of Chemistry, University of Sydney, NSW 2006, Australia.
* Corresponding author, Email: pittayat@su.ac.th
Received 4 Mar 2002, Accepted 4 Oct 2002
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