ScienceAsia 12 (1986): 239-242 |doi: 10.2306/scienceasia1513-1874.1986.12.239

ANTIMICROBIAL ACTIVITIES OF CHEMICAL CONSTITUENTS FROM GARCINIA MANGOSTANA LINN.

WILAWAN MAHABUSARAKAM,^a PICHAET WIRIYACHITRA^a,c AND SAOWALUK PHONGPAICHIT^b

ABSTRACT: Mangostin, gartanin, -mangostin, 1-isomangostin and 3-isomangostin isolated from Garcinia mangostana Linn. (Guttiferae) were investigated for their in vitro activities against Staphylococcus aureus both normal and penicillin-resistant strains. The best activity against both strains was found in mangostin. Mangostin, -mangostin and gartanin showed no activity against Candida albicans and Cryptococcus neoformans, but exhibited moderate activities against Trichophyton mentagrophytes and Microsporum gypseum.

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a Department of Chemistry, Prince of Songkla University, Hat Yai, Thailand.
b Department of Microbiology, Prince of Songkla University, Hat Yai, Thailand.
c To whom correspondence should be adressed.

Received 16 July 1986