ScienceAsia 10 (1984): 109-118 |doi: 10.2306/scienceasia1513-1874.1984.10.109

SUPPORTIVE EFFECTS OF MAGNESIUM CHLORIDE ON VIABILITY OF PLASMODIUM VIVAX IN VITRO

CHARIYA R. BROCKELMAN, RATCHAPIN LAOVANITCH and SASITHORN KAEWKES^a

ABSTRACT: Peripheral blood infected with Plasmodium vivax showed a decrease in parasite density and viability after the blood cells were washed conventionally in RPMI medium. Treatment of infected cells with a culture medium supplemented with 1000 mg/L MgCl₂ gave the most satisfactory yield. Marked differences in parasite viability were demonstrated in parasite schizogonic development in short-term cultures. Only the MgCl₂ itreated parasites were able to form merozoites.

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Department of Microbiology, Faculty of Science Mahidol University, Bangkok 10400, Thailand
a Present address: Department of Parasitology Faculty of Medicine, Khon Kaen. University, Khon Kaen 40200

Received 4 November 1983