 BackInvited Review ScienceAsia 12 (1986): 195-212 |doi: 10.2306/scienceasia1513-1874.1986.12.195
THE USE OF ANTHRACENE ADDUCTS IN THE SYNTHESIS OF NATURAL PRODUCTS*
YODHATHAI THEBTARANONTHABSTRACT: The development of the "anthracene adduct" for use in the synthesis of natural products is described. This stable intermediate is easily prepared from cheaply available starting materials and can be readily converted into various structure forms. This high versatility is demonstrated by its use in the synthesis of cyclopentenoid antibiotics (e.g. met~ylenomycins and sarkomycin), a-methylene lactones and acetylenic compounds. Thus the anthracene adduct provides a simple and economical route to compounds hitherto difficult to synthesize. Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok J 0400, Thailand Received 25 August 1986
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