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Short Report

ScienceAsia 8 (1982): 167-169 |doi: 10.2306/scienceasia1513-1874.1982.08.167

 

THE PICTET-SPENGLER REACTION OF ARYLGLYOXALS: A CONVENIENT SYNTHESIS OF 1-AROYL-1,2,3,4- TETRAHYDROISOQUINOLINES

 

SURACHAI NIMGIRAWATH and SOMSAK KAEWKET

ABSTRACT: The Pictet-Spengler reaction of arylglyoxals with 2-arylethylamines afforded the corresponding 1-aroyl-1,2,3,4-tetrahydro-isoquinolines in moderate yields.

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Department of Chemistry, Faculty of Science, Silpakorn University, Nakorn Pathom 73000, Thailand.

Received 23 May 1982