Research articles
ScienceAsia 51 (2023): 1-8 |doi:
10.2306/scienceasia1513-1874.2023.076
Yellowfin tuna (Thunnus albacares) collagen-based wound
dressing promotes wound closure by reducing tissue
inflammation
Aree Wanasuntronwonga, Pichayamon Maharatanawongb, Nattapon Rotpenpianc, Rudee Surarita,d,*,
Nuttawee Niamsirib,?
ABSTRACT: This study investigated the wound-closing properties of collagen-based dressings derived from various
biological sources. Specifically, we focused on the wound healing process and evaluated the effects of a wound
dressing made from collagen derived from the skin of yellowfin tuna. The results demonstrated that the yellowfin
based wound dressing (YCWD) promoted wound healing with good anti-infection properties during the inflammatory
phase of the wound healing process. Additionally, the YCWD did not interfere with or negatively impact the natural
sequence of events involved in wound healing and promoted complete wound closure. Overall, these findings indicate
that the YCWD promoted wound healing and closure with anti-infection effects. These results contribute to current
understandings of collagen-based dressings and future potential applications for wound control.
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| a |
Department of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok 10400 Thailand |
| b |
Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400 Thailand |
| c |
Department of Oral Biology and Occlusion, Faculty of Dentistry, Prince of Songkla University, Songkhla 90110
Thailand |
| d |
Faculty of Dentistry, Siam University, Bangkok 10160 Thailand |
* Corresponding author, E-mail: rudee.sur@mahidol.ac.th, nuttawee.nia@mahidol.ac.th
Received 10 Feb 2025, Accepted 4 Jul 2025
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